Рolymorphism study of cytochrome P450 gene in patients with glaucoma

Authors

  • B. B. Zhusipova ҚР БҒМ ҒК «Жалпы генетика және цитология институты»
  • O. Kh. Khamdiyeva ҚР БҒМ ҒК «Жалпы генетика және цитология институты»
  • E. R. Amzeyev ҚР БҒМ ҒК «Жалпы генетика және цитология институты»
  • N. B. Akhmatullina ҚР БҒМ ҒК «Жалпы генетика және цитология институты»

Keywords:

glaucoma, genetics, mutation, PCR, RFLP analysis

Abstract

Glaucoma – one of the widespread eye diseases bringing people to violation of visual functions, and also to a blindness. One of factors of development of glaucoma is heredity. Diagnostics at early stages is one of key factors of preservation of sight at the patient with primary open-angle glaucoma (POAG). 63 patients with POAG are investigated and the group of control made 25 people. Polymorphism gene cytochrome P450 associated with development of a hereditary form of glaucoma is revealed. Frequency of occurrence made 64% in Kazakhstan.

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Published

2016-01-14

Issue

Vol. 40 No. 1/2 (2014): Вестник Каз НУ Серия Экологическая

Section

ENVIRONMENTAL IMPACT OF ANTHROPOGENIC FACTORS AND ENVIRONMENTAL PROTECTION

How to Cite

Рolymorphism study of cytochrome P450 gene in patients with glaucoma. (2016). Eurasian Journal of Ecology, 40(1/2). https://bulletin-ecology.kaznu.kz/index.php/1-eco/article/view/616