Immunochemical characterization of monoclonal anti-idiotypic antibodies specific to antigens opisthorchiasis

Authors

  • G. S. Ramazanova ҚР БҒМ С.Сейфуллин атындағы Қазақ агротехникалық университеті
  • Zh. A. Suranshiev ҚР БҒМ С.Сейфуллин атындағы Қазақ агротехникалық университеті
  • Sh. S. Serikova ҚР БҒМ С.Сейфуллин атындағы Қазақ агротехникалық университеті

Keywords:

opisthorchiasis, diagnostics, excretory-secretory antigen, enzyme immunoassay, hybridoma, monoclonal antibodies, anti-idiotypic antibodies.

Abstract

Great interest is the use of "internal image" of the antigen, i.e. anti-idiotypic antibodies (AIAB) against Fab-antibody fragments that are specific to ES-AG epitopes. The aim of this research was to determine the possibility of using anti-idiotypes as an antigen in ELISA for serological diagnosis of Opisthorchiasis. To do this, were conducted determine immunochemical properties of anti-idiotype antibodies. The results of research suggest the possibility of using Hybridomas 4H10 as an antigen in the development of immunoassays for the diagnosis of Opisthorchiasis.

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Issue

Vol. 40 No. 1/2 (2014): Вестник Каз НУ Серия Экологическая

Section

ENVIRONMENTAL IMPACT OF ANTHROPOGENIC FACTORS AND ENVIRONMENTAL PROTECTION

How to Cite

Immunochemical characterization of monoclonal anti-idiotypic antibodies specific to antigens opisthorchiasis. (2016). Eurasian Journal of Ecology, 40(1/2). https://bulletin-ecology.kaznu.kz/index.php/1-eco/article/view/638