GENETIC ANALYSIS OF NUCLEOPROTEIN OF A/H3N8 INFLUENZA VIRUS OF ASIAN AND EUROPEAN ORIGIN ISOLATED IN 2018

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DOI:

https://doi.org/10.26577/EJE.2024.v80.i3-010
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Abstract

This paper presents the results of a genetic analysis of the nucleoprotein gene (NP) of two strains of avian influenza virus isolated in the territory of the Republic of Kazakhstan in 2018 near small lakes (Alua and Zaimishche) of the North Kazakhstan region. These strains showed the presence of 54 in the nucleotide and 4 substitutions in the amino acid sequence, thereby significantly distancing themselves from each other. In phylogenetic analysis, the strain A/northern shoveler/North-Kazakhstan/20/2018(H3N8) showed the greatest relationship with strains from Europe, the homology between strains showed 96-97%. The second strain A/garganey/North Kazakhstan/45/2018(H3N8) showed genetic similarity with strains from Asia, the NP gene identity was 99%.

Keywords: influenza, virus, NP, avian IAV, H3N8, vRNP, RNA

Author Biographies

Aibarys Melisbek, Research Institute for Biological Safety Problems, Jambyl Region, Guardeyskiy uts, Kazakhstan

Melisbek Aibarys  - Junior Researcher at the Scientific Research Institute of Problems of Biological Safety,
PhD Student at the Department of Molecular Biology and Genetics, al-Farabi Kazakh National University
(Guardeyskiy, Kazakhstan, e-mail: aibarysmmm@gmail.com)

Saltanat Kendirbayeva, Kyrgyz State University, Bishkek, Kyrgyzstan

Kendirbayeva Saltanat  - Associate Professor of the Department of Biodiversity Faculty of Biology and Chemistry Kyrgyz State University named after I. Arabayev, Candidate of Biological Sciences
(Bishkek, Kyrgyzstan, e-mail: santaken999@gmail.com)

Bekbolat Userbayev , Research Institute for Biological Safety Problems, Jambyl Region, Guardeyskiy uts, Kazakhstan

Userbayev Bekbolat  - Senior Researcher at the Scientific Research Institute of Problems of Biological Safety (Guardeyskiy, Kazakhstan, e-mail: b.usserbayev@biosafety.kz)

Meirzhan Shirinbekov, Research Institute for Biological Safety Problems, Jambyl Region, Guardeyskiy uts, Kazakhstan

Shirinbekov Meirzhan  - Junior Researcher at the Scientific Research Institute of Problems of Biological Safety (Guardeyskiy, Kazakhstan, e-mail: meirzhan1016@mail.ru)

Gauhar Akbolat , Research Institute for Biological Safety Problems, Jambyl Region, Guardeyskiy uts, Kazakhstan

Akbolat Gauhar  - Master’s Student at the Faculty of Biology and Biotechnology al-Farabi Kazakh National University(Almaty, Kazakhstan, e-mail: a.gauhar01@mail.ru)

Yerbol Burashev, Research Institute for Biological Safety Problems, Jambyl Region, Guardeyskiy uts, Kazakhstan

Burashev Yerbol  - Head of Laboratory, PhD, at the Scientific Research Institute of Problems of Biological Safety (Guardeyskiy, Kazakhstan, e-mail: e.burashev@biosafety.kz)

Nurlan Kozhabergenov, Research Institute for Biological Safety Problems, Jambyl Region, Guardeyskiy uts, Kazakhstan

Kozhabergenov Nurlan  - Senior Researcher at the Scientific Research Institute of Problems of Biological Safety (Guardeyskiy, Kazakhstan, e-mail: n.kozhabergenov@biosafety.kz)

Araylym Bopi, Research Institute for Biological Safety Problems, Jambyl Region, Guardeyskiy uts, Kazakhstan

Bopi Araylym - Researcher at the Scientific Research Institute of Problems of Biological Safety
(Guardeyskiy, Kazakhstan, e-mail: a.bopi@biosafety.kz)

Kaynar Barakbaev, Research Institute for Biological Safety Problems, Jambyl Region, Guardeyskiy uts, Kazakhstan

Barakbayev Kaynar  - Head of Laboratory at the Scientific Research Institute of Problems of Biological Safety, Candidate of Veterinary Sciences (Guardeyskiy, Kazakhstan, e-mail: k.barakbayev@biosafety.kz)

Aziz Nakhanov

Nakhanov Aziz - Head of Laboratory at the Scientific Research Institute of Problems of Biological Safety, Candidate of Biological Sciences (Guardeyskiy, Kazakhstan, e-mail: a.nakhanov@biosafety.kz)

Mukhit Orynbayev, Research Institute for Biological Safety Problems, Jambyl Region, Guardeyskiy uts, Kazakhstan

Orynbayev Mukhit  - Chief Researcher at the Scientific Research Institute of Problems of Biological Safety Academician of the National Academy of Sciences, Professor, Candidate of Veterinary Sciences
(Guardeyskiy, Kazakhstan, e-mail: omb65@mail.ru)

Kulyaisan Sultankulova

Sultankulova Kulyaisan - Head of Laboratory at the Scientific Research Institute of Problems of Biological Safety, Professor, Candidate of Biological Sciences (Guardeyskiy, Kazakhstan, e-mail: k.sultankulova@biosafety.kz)

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How to Cite

Melisbek А., Kendirbayeva С. ., Userbayev Б., Shirinbekov М., Akbolat Г., Burashev Е., Kozhabergenov Н., Bopi А., Barakbaev К., Nakhanov А., Orynbayev М. ., & Sultankulova К. (2024). GENETIC ANALYSIS OF NUCLEOPROTEIN OF A/H3N8 INFLUENZA VIRUS OF ASIAN AND EUROPEAN ORIGIN ISOLATED IN 2018. Eurasian Journal of Ecology, 80(3). https://doi.org/10.26577/EJE.2024.v80.i3-010

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CURRENT PROBLEMS OF CONSERVATION OF BIOLOGICAL DIVERSITY